Home Depot Inc vs McKesson Corporation — how do they compare? Home Depot Inc trades at $333.56 (market cap $332.08B), while McKesson Corporation trades at $829.95 (market cap $97.35B). The key difference: Home Depot Inc is far larger — about 3.4× McKesson Corporation's market cap, and Home Depot Inc pays the higher dividend (2.8%). Which is the better fit depends on your goals.
| HD | MCK | |
|---|---|---|
Market Cap | $332.08B | $97.35B |
Sector | Consumer Cyclical | Health |
52-Week High | $423.42 | $995.69 |
52-Week Low | $297.51 | $659.01 |
Enterprise Value | $393.64B | $101.98B |
Dividend Yield | 2.8% | 0.39% |
Signals from Pluang's Aura AI — not financial advice
Home Depot (HD) trades at $338.87, down 2.63% amid bearish technical signals and mixed fundamental performance. The stock shows strong profitability with 8.41% net margin and 128.38% ROE, but faces margin compression with profit margins declining from 10.87% in 2022 to 9.28% in 2025. Recent earnings show mixed results with Q3 2025 missing expectations while Q4 2025 and Q1 2026 beat estimates. Technical analysis indicates bearish momentum with key support at $321 and resistance at $343.
Despite near-term headwinds, HD maintains strong analyst support with 59% buy ratings and $370.59 consensus target, representing 9.4% upside. The company's robust cash flow generation and Pro business growth provide long-term stability, though rising mortgage rates and housing market sensitivity pose significant risks to near-term performance.
McKesson Corporation (MCK) trades at $831.60, down 1.16% on the day, with a bullish technical signal and positive earnings momentum after beating estimates for three consecutive quarters. The stock shows strong analyst support with an 80% buy rating and a consensus price target of $932.83, implying potential upside. Revenue growth is robust, reaching $359.05 billion in 2025, though net margins remain thin at 1.18%. Cash flow from operations improved to $6.09 billion in 2025, supporting financial stability.
The outlook for MCK is positive, driven by earnings beats, analyst optimism, and solid cash generation. Key opportunities include growth in specialty pharma and oncology services. Risks involve policy uncertainties, competitive pressures, and execution challenges. The stock's current price near key support at $829 suggests a critical level for near-term direction.
Trailing returns across standard periods
Home Depot is the world's largest home improvement specialty retailer, operating more than 2,300 warehouse-format stores offering more than 30,000 products in store and 1 million products online in the United States, Canada, and Mexico. Its stores offer numerous building materials, home improvement products, lawn and garden products, and decor products and provide various services, including home improvement installation services and tool and equipment rentals. The acquisition of distributor Interline Brands in 2015 allowed Home Depot to enter the maintenance, repair, and operations business, which has been expanded through the tie-up with HD Supply (2020). The addition of the Company Store brought textile exposure to Home Depot's lineup.
Read more on HD →McKesson is a leading wholesaler of branded, generic, and specialty pharmaceutical products to pharmacies (retail chains, independent, and mail order), hospitals networks, and healthcare providers. Along with AmerisourceBergen and Cardinal Health, the three account for well over 90% of the U.S. pharmaceutical wholesale industry. McKesson is currently divesting from its pharmaceutical wholesale and distribution in Europe and Canada in order to redeploy capital to strategic growth areas in the U.S. (oncology network and ecosystem, and biopharma services). Additionally, the company supplies medical-surgical products and equipment to healthcare facilities and provides a variety of technology solutions for pharmacies.
Read more on MCK →