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Compare Home Depot Inc (HD) vs Illumina, Inc. (ILMN) Price & Performance

Home Depot IncTrade
Illumina, Inc.Trade

Price performance (Past 24H)

Key statistics

Home Depot Inc vs Illumina, Inc. — how do they compare? Home Depot Inc trades at $332.73 (market cap $332.08B), while Illumina, Inc. trades at $189.49 (market cap $27.94B). The key difference: Home Depot Inc is far larger — about 11.9× Illumina, Inc.'s market cap, and Home Depot Inc pays a 2.8% dividend while Illumina, Inc. pays none. Which is the better fit depends on your goals.

HDILMN
Market Cap
$332.08B$27.94B
Sector
Consumer CyclicalHealth
52-Week High
$423.42$194.33
52-Week Low
$297.51$91.00
Enterprise Value
$393.64B$29.33B
Dividend Yield
2.8%

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Home Depot Inc

Home Depot (HD) trades at $330.95, down 2.34% on the day, approaching its 52-week low amid broader market weakness in home improvement stocks. The company reported mixed quarterly earnings with a Q3 2025 miss but subsequent beats, while maintaining solid profitability with 8.41% net margins and strong ROE of 128.38%. Technical indicators show a bearish trend with key support at $321, while analysts maintain a predominantly bullish outlook with a $370.59 consensus price target representing 12% upside potential.

The outlook balances near-term headwinds from weakening big-ticket demand and rising mortgage rates against long-term strengths in Pro segment growth and housing market tailwinds. Investment opportunities include the stock's discount to analyst targets and resilient business model, while risks include margin pressure from investments, competitive threats, and sensitivity to housing market cycles.

Illumina, Inc.

Illumina (ILMN) trades at $185.36, down 0.69% on the day, with a bullish technical signal from moving averages. The stock shows strong profitability with a 19.42% net income margin and has beaten EPS estimates for three consecutive quarters. Recent news highlights expansion of the Billion Cell Atlas program and upcoming Q2 2026 earnings on July 30.

Outlook remains positive with 51% analyst buy ratings, though the current price exceeds the $178 consensus target. Key risks include competitive pressure from Roche's new sequencer and China market weakness. Earnings growth and cost control initiatives support upside potential, but valuation multiples suggest limited near-term appreciation.

Returns comparison

Trailing returns across standard periods

Top news

Latest headlines on both assets

About Home Depot Inc

Home Depot is the world's largest home improvement specialty retailer, operating more than 2,300 warehouse-format stores offering more than 30,000 products in store and 1 million products online in the United States, Canada, and Mexico. Its stores offer numerous building materials, home improvement products, lawn and garden products, and decor products and provide various services, including home improvement installation services and tool and equipment rentals. The acquisition of distributor Interline Brands in 2015 allowed Home Depot to enter the maintenance, repair, and operations business, which has been expanded through the tie-up with HD Supply (2020). The addition of the Company Store brought textile exposure to Home Depot's lineup.

Read more on HD

About Illumina, Inc.

Illumina provides tools and services to analyze genetic material with life science and clinical lab applications. The company generates over 90% of its revenue from sequencing instruments, consumables, and services. Illumina's high-throughput technology enables whole genome sequencing in humans and other large organisms. Its lower throughput tools enable applications that require smaller data outputs, such as viral and cancer tumor screening. Illumina also sells microarrays (less than 10% of sales) that enable lower-cost, focused genetic screening with primarily consumer and agricultural applications.

Read more on ILMN