GSK plc vs Upstart Holdings Inc — how do they compare? GSK plc trades at $52.4 (market cap $101.34B), while Upstart Holdings Inc trades at $31.56 (market cap $3.02B). The key difference: GSK plc is far larger — about 33.6× Upstart Holdings Inc's market cap, and GSK plc pays a 3.49% dividend while Upstart Holdings Inc pays none. Which is the better fit depends on your goals.
| GSK | UPST | |
|---|---|---|
Market Cap | $101.34B | $3.02B |
Sector | Health | Financials |
52-Week High | $61.18 | $84.13 |
52-Week Low | $36.20 | $24.22 |
Enterprise Value | $121.95B | — |
Dividend Yield | 3.49% | — |
Signals from Pluang's Aura AI — not financial advice
GSK's stock trades at $51.25, down 1.99% on the day, with a bearish technical signal from moving averages. Fundamentally, the company shows strong profitability with a 17.78% net margin and 36.42% ROE, supported by a consistent earnings beat history. Recent positive clinical trial results for Jemperli in rectal cancer and FDA approval for Utebzi highlight pipeline progress. Valuation appears reasonable with a P/E of 13.71 and EV/EBITDA of 9.16.
The outlook balances a solid core business and promising oncology pipeline against a mixed analyst consensus and near-term cash flow pressures. Key opportunities lie in execution of new drug launches and the upcoming CEO strategy update, while risks include clinical trial setbacks, competitive pressures, and integration of potential acquisitions like Nuvalent.
Upstart Holdings (UPST) trades at $31.72, up 0.83% on the day, with a bearish technical signal and mixed recent earnings. The company reported a significant revenue rebound to $1.02B in 2025 and a return to profitability with $53.60M net income, but Q1 2026 saw an unexpected EPS miss. Analyst consensus is split between Buy and Hold, with a $42.00 price target suggesting potential upside. Recent news highlights the company's AI lending platform expansion and a key $600M funding deal.
The outlook hinges on execution of its AI-driven lending model amid margin pressures. Investment opportunity lies in the company's revenue growth and expanding product lines, but risks include volatile cash flows, high debt levels, and sensitivity to funding markets and economic cycles. The stock's high P/E ratio of 77.05 demands sustained high growth to justify valuation.
Trailing returns across standard periods
Latest headlines on both assets
In the pharmaceutical industry, GSK ranks as one of the largest firms by total sales. The company wields its might across several therapeutic classes, including respiratory, cancer, and antiviral, as well as vaccines. GSK uses joint ventures to gain additional scale in certain markets like HIV.
Read more on GSK →Upstart Holdings Inc provides credit services. The company provides a proprietary, cloud-based, artificial intelligence lending platform. The platform aggregates consumer demand for loans and connects it to the network of Upstart AI-enabled bank partners. The revenue of the company is primarily comprised of fees paid by banks.
Read more on UPST →