Gilead Sciences, Inc. vs Opendoor Technologies Inc — how do they compare? Gilead Sciences, Inc. trades at $135.99 (market cap $164.99B), while Opendoor Technologies Inc trades at $3.58 (market cap $3.36B). The key difference: Gilead Sciences, Inc. is far larger — about 49.1× Opendoor Technologies Inc's market cap, and Gilead Sciences, Inc. pays a 2.47% dividend while Opendoor Technologies Inc pays none. Which is the better fit depends on your goals.
| GILD | OPEN | |
|---|---|---|
Market Cap | $164.99B | $3.36B |
Sector | Health | Real Estate |
52-Week High | $155.80 | $10.52 |
52-Week Low | $110.56 | $2.31 |
Enterprise Value | $188.06B | $4.43B |
Dividend Yield | 2.47% | — |
Signals from Pluang's Aura AI — not financial advice
Gilead Sciences (GILD) trades at $133.21, up 1.8% in the last session, with a bullish technical outlook and strong analyst support. Recent Q2 2026 results showed a revenue beat despite a net loss driven by acquisition costs, with HIV drug sales and pipeline progress fueling raised full-year guidance. The stock exhibits robust cash flow from operations and a high gross margin, though negative net income and elevated debt levels present fundamental concerns.
The outlook is positive based on raised sales guidance and pipeline momentum, but risks include patent cliffs for key HIV drugs by the mid-2030s and integration challenges from recent acquisitions. With a consensus price target of $151.22 implying 13.5% upside, Wall Street sentiment is bullish, though investors should weigh growth prospects against execution and regulatory risks.
Opendoor Technologies (OPEN) trades at $3.485, up 1.16% on the day, but remains in a bearish technical trend with weak fundamentals. Revenue has declined from $15.6B in 2022 to $4.37B in 2025, with persistent net losses and a negative net income margin of -46.74%. Recent Q2 2026 earnings missed expectations, and cash flow volatility adds to operational challenges. The stock faces headwinds from a sluggish housing market and high interest rates, as reflected in negative analyst sentiment and a consensus price target of $3.58.
The outlook for OPEN is cautious due to ongoing losses, competitive pressures, and macroeconomic uncertainty. While the low P/S ratio of 0.95 may attract value seekers, significant execution risk and debt levels pose threats. Investor sentiment is predominantly bearish, with 65% of analysts rating Hold. Recovery hinges on sustainable margin improvement and housing market stabilization, but near-term volatility is expected.
Trailing returns across standard periods
Latest headlines on both assets
Gilead Sciences develops and markets therapies to treat life-threatening infectious diseases, with the core of its portfolio focused on HIV and hepatitis B and C. The acquisitions of Corus Pharma, Myogen, CV Therapeutics, Arresto Biosciences, and Calistoga have broadened this focus to include pulmonary and cardiovascular diseases and cancer. Gilead's acquisition of Pharmasset brought rights to hepatitis C drug Sovaldi, which is also part of combination drug Harvoni, and the Kite, Forty Seven, and Immunomedics acquisitions boost Gilead's exposure to cell therapy and noncell therapy in oncology.
Read more on GILD →Opendoor Technologies Inc is a digital platform for residential real estate. This platform enables customers to buy and sell houses online. It generates revenue through home sales, along with other revenue from real estate services.
Read more on OPEN →