Gilead Sciences, Inc. vs Old Dominion Freight Line Inc — how do they compare? Gilead Sciences, Inc. trades at $133.6 (market cap $163.51B), while Old Dominion Freight Line Inc trades at $233.52 (market cap $46.84B). The key difference: Gilead Sciences, Inc. is far larger — about 3.5× Old Dominion Freight Line Inc's market cap, and Gilead Sciences, Inc. pays the higher dividend (2.49%). Which is the better fit depends on your goals.
| GILD | ODFL | |
|---|---|---|
Market Cap | $163.51B | $46.84B |
Sector | Health | Industrials |
52-Week High | $155.80 | $248.73 |
52-Week Low | $108.22 | $126.29 |
Enterprise Value | $178.05B | $46.59B |
Dividend Yield | 2.49% | 0.52% |
Signals from Pluang's Aura AI — not financial advice
No Aura AI signal available yet.
Old Dominion Freight Line (ODFL) trades at $228.61, down 1.84% on the day, with a bullish technical signal from moving averages. The company maintains strong profitability with 18.46% net margins and has beaten earnings estimates for three consecutive quarters. Recent news highlights Amazon's expansion into LTL shipping creating competitive pressure, while the company announced a $0.29 quarterly dividend payable in June 2026.
ODFL presents a mixed outlook with excellent operational efficiency and debt-free balance sheet offset by premium valuation metrics. The stock trades near analyst consensus target of $233.67 with improving freight market conditions expected in 2026. Key risks include competitive threats from Amazon, cyclical industry exposure, and valuation concerns at current P/E of 47.02.
Trailing returns across standard periods
Gilead Sciences develops and markets therapies to treat life-threatening infectious diseases, with the core of its portfolio focused on HIV and hepatitis B and C. The acquisitions of Corus Pharma, Myogen, CV Therapeutics, Arresto Biosciences, and Calistoga have broadened this focus to include pulmonary and cardiovascular diseases and cancer. Gilead's acquisition of Pharmasset brought rights to hepatitis C drug Sovaldi, which is also part of combination drug Harvoni, and the Kite, Forty Seven, and Immunomedics acquisitions boost Gilead's exposure to cell therapy and noncell therapy in oncology.
Read more on GILD →Old Dominion Freight Line is the fourth-largest less-than-truckload carrier in the United States, with more than 240 service centers and 9,200-plus tractors. OD is by far one of the most disciplined and efficient providers in the trucking industry, and its profitability and capital returns stand head and shoulders above its peers. Strategic initiatives revolve around increasing network density through market share gains and maintaining industry-leading service via consistent infrastructure investment.
Read more on ODFL →