Gilead Sciences, Inc. vs Hewlett Packard Enterprise Co — how do they compare? Gilead Sciences, Inc. trades at $135.6 (market cap $163.51B), while Hewlett Packard Enterprise Co trades at $45.01 (market cap $62.75B). The key difference: Gilead Sciences, Inc. is far larger — about 2.6× Hewlett Packard Enterprise Co's market cap, and Gilead Sciences, Inc. pays the higher dividend (2.49%). Which is the better fit depends on your goals.
| GILD | HPE | |
|---|---|---|
Market Cap | $163.51B | $62.75B |
Sector | Health | Technology |
52-Week High | $155.80 | $56.14 |
52-Week Low | $108.22 | $19.81 |
Enterprise Value | $178.05B | $78.71B |
Dividend Yield | 2.49% | 1.2% |
Signals from Pluang's Aura AI — not financial advice
Gilead Sciences (GILD) trades at $133.30, up 2.51% today, with strong technical momentum above key support at $130. The company demonstrates robust fundamentals with a 30.99% net income margin and consistent earnings beats in recent quarters. Recent FDA and EC approvals for Trodelvy in metastatic triple-negative breast cancer highlight growth potential beyond its HIV franchise.
Outlook remains positive with a consensus price target of $152.83 offering 14.6% upside, though risks include patent expirations and competitive pressures. The stock presents a compelling opportunity driven by oncology expansion and strong cash flow generation, supported by overwhelming analyst bullish sentiment.
HPE stock declined 8.45% to $45.37 amid a broader AI hardware sector pullback, though technical indicators remain bullish with strong support at $45. The company shows solid fundamentals with three consecutive earnings beats and robust AI infrastructure demand driving a record $6B backlog. Revenue grew to $34.3B in 2025 while maintaining a 33.9% gross margin, though net income dropped significantly to $57M due to acquisition-related costs.
HPE presents a compelling opportunity with analyst consensus target of $69.69 (54% upside) and strong AI infrastructure positioning, but faces execution risks from the Juniper integration and volatile cash flow trends. The stock's current valuation at 44.29 P/E appears elevated relative to historical norms, requiring careful monitoring of margin expansion and debt management.
Trailing returns across standard periods
Latest headlines on both assets
Gilead Sciences develops and markets therapies to treat life-threatening infectious diseases, with the core of its portfolio focused on HIV and hepatitis B and C. The acquisitions of Corus Pharma, Myogen, CV Therapeutics, Arresto Biosciences, and Calistoga have broadened this focus to include pulmonary and cardiovascular diseases and cancer. Gilead's acquisition of Pharmasset brought rights to hepatitis C drug Sovaldi, which is also part of combination drug Harvoni, and the Kite, Forty Seven, and Immunomedics acquisitions boost Gilead's exposure to cell therapy and noncell therapy in oncology.
Read more on GILD →Hewlett Packard Enterprise is an information technology vendor that provides hardware and software to enterprises. Its primary product lines are compute servers, storage arrays, and networking equipment.
Read more on HPE →