Compare EPAM Systems Inc (EPAM) vs Vertex Pharmaceuticals Incorporated (VRTX) Price & Performance
Price performance (Past 24H)
Key statistics
Key statistics
EPAM Systems Inc vs Vertex Pharmaceuticals Incorporated — how do they compare? EPAM Systems Inc trades at $87.38 (market cap $4.49B), while Vertex Pharmaceuticals Incorporated trades at $486.97 (market cap $121.09B). The key difference: Vertex Pharmaceuticals Incorporated is far larger — about 27× EPAM Systems Inc's market cap, and Vertex Pharmaceuticals Incorporated is trading nearer its 52-week high, EPAM Systems Inc nearer its low. Which is the better fit depends on your goals.
| EPAM | VRTX | |
|---|---|---|
Market Cap | $4.49B | $121.09B |
Sector | Technology | Health |
52-Week High | $221.40 | $529.59 |
52-Week Low | $76.04 | $366.54 |
Enterprise Value | $3.74B | $115.83B |
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
EPAM Systems trades at $88.59, up 4.84% today, with a bearish technical signal but strong fundamentals including a P/E of 12.35 and P/S of 0.86. Recent earnings beats and a consensus analyst price target of $128.55 suggest undervaluation, while cash flow trends show operational strength despite a net decline in 2026 projections. The stock faces headwinds from AI sector volatility but benefits from strategic partnerships and AI-native revenue growth.
The outlook for EPAM is cautiously optimistic, with significant upside potential based on analyst targets, though risks include competitive pressures and macroeconomic uncertainty. Investment opportunity lies in its valuation discount and digital engineering expertise, but investors should monitor execution on AI initiatives and sector sentiment shifts for near-term direction.
Vertex Pharmaceuticals (VRTX) trades at $481.35, up 1.06% today, and is near its 52-week high. The stock shows a bullish technical signal with support at $471 and resistance at $482. Fundamentally, the company reported strong 2025 results with $12.0B revenue and $4.0B net income, though 2024 saw a loss. The recent $10B acquisition of Crinetics Pharmaceuticals aims to expand its endocrinology pipeline, potentially adding $5B in peak sales.
Outlook remains positive with analyst consensus at 'Buy' and a $538 price target, implying 12% upside. Key risks include integration challenges from the Crinetics deal and reliance on cystic fibrosis treatments. Earnings growth and pipeline expansion are primary catalysts, but investors should monitor execution on acquisitions and competitive pressures in biotech.
Returns comparison
Trailing returns across standard periods
Returns comparison
Trailing returns across standard periods
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About EPAM Systems Inc
EPAM Systems Inc provides software product development and digital platform engineering services to clients located around the world. The company services include Software Product Development, Custom Application Development, Application Testing, Enterprise Application Platforms, Application Maintenance, and Support and Infrastructure Management. The company focuses on innovative and scalable software solutions. The company uses industry standard and custom developed technology, tools, and platforms to deliver results to handle business challenges. The company primarily offers its solutions in the following industries: financial services, travel and consumer, software and hi-tech, life sciences and healthcare. The majority of revenue is generated from North American clients.
Read more on EPAM →About Vertex Pharmaceuticals Incorporated
Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio for cystic fibrosis, where Vertex therapies remain the standard of care globally. In addition to its focus on cystic fibrosis, Vertex is diversifying its pipeline through gene-editing therapies such as CTX001 for beta-thalassemia and sickle-cell disease, small-molecule inhibitors targeting acute and chronic pain using non-opioid treatments, and small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
Read more on VRTX →
