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Compare Domino's Pizza, Inc. (DPZ) vs Vertex Pharmaceuticals Incorporated (VRTX) Price & Performance

Domino's Pizza, Inc.Trade
Vertex Pharmaceuticals IncorporatedTrade

Price performance (Past 24H)

Key statistics

Domino's Pizza, Inc. vs Vertex Pharmaceuticals Incorporated — how do they compare? Domino's Pizza, Inc. trades at $308.66 (market cap $10.03B), while Vertex Pharmaceuticals Incorporated trades at $503.25 (market cap $128.16B). The key difference: Vertex Pharmaceuticals Incorporated is far larger — about 12.8× Domino's Pizza, Inc.'s market cap, and Domino's Pizza, Inc. pays a 2.63% dividend while Vertex Pharmaceuticals Incorporated pays none. Which is the better fit depends on your goals — on Pluang, investors hold Domino's Pizza, Inc. for 106 Days and Vertex Pharmaceuticals Incorporated for 120 Days on average.

DPZVRTX
Market Cap
$10.03B$128.16B
Volume
892,489806,603
Sector
Consumer CyclicalHealth
52-Week High
$438.42$557.96
52-Week Low
$282.89$407.37
Typical Hold Time
106 Days120 Days
Enterprise Value
$14.99B$122.29B
Dividend Yield
2.63%—

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Domino's Pizza, Inc.

Domino's Pizza (DPZ) trades at $308.65, up 1.91% today, with a bullish technical signal despite recent earnings misses. Revenue has grown steadily to $4.94B in 2025, with a net margin of 11.86%, though the stock faces headwinds from high debt levels and flat dividend growth. Analyst consensus is a Buy with a $373 price target, but news highlights store closures and competitive pressures.

The outlook is mixed: strong cash flow and brand strength support upside, but debt burden and margin pressure pose risks. Investors should weigh analyst optimism against execution challenges in a competitive sector.

Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals (VRTX) trades at $503.25, showing modest daily gains of 0.16%. The stock faces bearish technical signals with mixed earnings performance, missing Q4 2025 and Q2 2026 EPS estimates but beating Q1 2026. Strong fundamentals include 86% gross margins and 35% net income margins, with revenue projected to grow from $12B to $12.6B in 2026. Recent positive Phase II data for kidney disease drug inaxaplin highlights pipeline progress.

Outlook remains positive with 84% analyst buy ratings and $573 consensus target offering 14% upside. Key risks include reliance on cystic fibrosis franchise and competitive pressures. Earnings consistency and pipeline execution are critical for sustained growth amid current technical weakness.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

DPZ
100% Buy0% Sell
Avg holding period · 106 Days
VRTX
100% Buy0% Sell
Avg holding period · 120 Days

Top news

Latest headlines on both assets

About Domino's Pizza, Inc.

Domino's is a restaurant operator and franchiser with nearly 19,000 global stores across more than 90 international markets at the end of 2021. The firm generates revenue through the sales of pizza, wings, salads, and sandwiches at company-owned stores, royalty and marketing contributions from franchise-operated stores, and its network of 25 domestic (and five Canadian) dough manufacturing and supply chain facilities, which centralize purchasing, preparation, and last-mile delivery for the firm's U.S. and Canadian restaurants. With roughly $17.7 billion in 2021 system sales, Domino's is the largest player in the global pizza market, ahead of Pizza Hut, Papa John's, and Little Caesars.

Read more on DPZ →

About Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio for cystic fibrosis, where Vertex therapies remain the standard of care globally. In addition to its focus on cystic fibrosis, Vertex is diversifying its pipeline through gene-editing therapies such as CTX001 for beta-thalassemia and sickle-cell disease, small-molecule inhibitors targeting acute and chronic pain using non-opioid treatments, and small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.

Read more on VRTX →