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Compare DigitalOcean Holdings Inc (DOCN) vs Twist Bioscience Corp (TWST) Price & Performance

DigitalOcean Holdings IncTrade
Twist Bioscience CorpTrade

Price performance (Past 24H)

Key statistics

DigitalOcean Holdings Inc vs Twist Bioscience Corp — how do they compare? DigitalOcean Holdings Inc trades at $125.66 (market cap $14.57B), while Twist Bioscience Corp trades at $157 (market cap $10.08B). The key difference: DigitalOcean Holdings Inc is the larger of the two by market cap, and Twist Bioscience Corp is trading nearer its 52-week high, DigitalOcean Holdings Inc nearer its low. Which is the better fit depends on your goals — on Pluang, investors hold DigitalOcean Holdings Inc for 43 Days and Twist Bioscience Corp for 27 Days on average.

DOCNTWST
Market Cap
$14.57B$10.08B
Volume
2,261,7864,229,037
Sector
TechnologyHealth
52-Week High
$181.29$205.00
52-Week Low
$37.30$25.45
Typical Hold Time
43 Days27 Days
Enterprise Value
$15.33B$10.01B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

DigitalOcean Holdings Inc

DigitalOcean trades at $127.28, down 2.89% today, with strong technical support at $126 and resistance at $130. The company shows robust revenue growth from $576M in 2022 to $901M in 2025, with net income turning positive to $259M. Recent AI-focused product launches including Agent Droplets and Managed Agents position the company for continued growth in cloud services.

Despite high valuation multiples (P/E 57.85, P/S 14.34), analyst consensus remains bullish with a $172.73 price target representing 36% upside. Key risks include capital intensity from expansion and high debt levels, while institutional accumulation and consistent earnings beats support the growth narrative.

Twist Bioscience Corp

TWST trades at $155.65, down 6.78% today, reflecting a bearish technical signal and recent earnings misses. Revenue growth is strong, rising to $376.57M in 2025, but profitability remains elusive with a net income margin of -31.66%. The company's partnership with Lilly TuneLab for AI-driven drug discovery has generated positive news flow, yet cash flow remains negative, and the stock trades at elevated valuation multiples like P/S of 22.01.

The outlook is mixed: strong analyst buy-side consensus (73% Buy) and strategic AI partnerships offer growth potential, but persistent losses, high cash burn, and bearish technicals pose significant risks. Investors face a trade-off between long-term innovation prospects and near-term financial instability.

Returns comparison

Trailing returns across standard periods

Investor sentiment on Pluang

What Pluang investors did over the last 30 days

DOCN
100% Buy0% Sell
Avg holding period · 43 Days
TWST
37% Buy63% Sell
Avg holding period · 27 Days

Top news

Latest headlines on both assets

About DigitalOcean Holdings Inc

DigitalOcean Holdings Inc is a cloud computing platform offering on-demand infrastructure and platform tools for developers, start-ups and small and medium-sized businesses. The customers use the platform for a wide range of cases, such as web and mobile applications, website hosting, e-commerce, media and gaming, personal web projects, and managed services, among many others. The group has a business presence in North America, Europe, Asia and other countries.

Read more on DOCN →

About Twist Bioscience Corp

Twist Bioscience Corp is a synthetic biology company. It develops a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's DNA synthesis platform utilizes a proprietary semiconductor-based synthetic DNA manufacturing process that synthesizes DNA on silicon instead of on traditional well plastic plates to enable the production of high-quality synthetic DNA faster and affordable as well as overcomes inefficiencies. Powering cost-effective, rapid high-throughput synthesis, it enables researchers to rapidly realize opportunities ahead. Geographically, it derives a majority of revenue from the United States.

Read more on TWST →