Crispr Therapeutics AG vs Seagate Technology Holdings PLC — how do they compare? Crispr Therapeutics AG trades at $50.54 (market cap $4.97B), while Seagate Technology Holdings PLC trades at $875 (market cap $198.72B). The key difference: Seagate Technology Holdings PLC is far larger — about 40× Crispr Therapeutics AG's market cap, and Seagate Technology Holdings PLC pays a 0.34% dividend while Crispr Therapeutics AG pays none. Which is the better fit depends on your goals.
| CRSP | STX | |
|---|---|---|
Market Cap | $4.97B | $198.72B |
Sector | Health | Technology |
52-Week High | $76.78 | $1.09K |
52-Week Low | $44.34 | $146.59 |
Enterprise Value | $3.32B | $201.75B |
Dividend Yield | — | 0.34% |
Signals from Pluang's Aura AI — not financial advice
CRSP trades at $50.63, down 5.1% over 24 hours, amid a bearish technical signal. The company shows deep losses with a net income margin of -56,853.4% in 2025 and negative cash flow from operations. However, analyst consensus remains optimistic with a $74.50 price target, and recent news highlights FDA approval for Casgevy, expanding its gene therapy market.
The outlook hinges on commercial execution of Casgevy and pipeline progress, offering high growth potential in gene editing. Key risks include sustained cash burn, competitive pressures, and regulatory hurdles. Despite current financial challenges, strong analyst buy ratings suggest confidence in long-term value.
STX trades at $860.66, down 5.46% over 24 hours, with a bearish technical signal and elevated valuation ratios (P/E 81.66, P/S 17.61). Recent earnings beats (Q1 2026 EPS $4.10 vs. $3.51 expected) and strong revenue growth to $9.10B in 2025 highlight operational momentum, though negative shareholder equity and high debt pose balance sheet concerns. Analyst consensus remains bullish with a $987.86 price target, supported by AI-driven storage demand upgrades from Wells Fargo on July 10, 2026.
Outlook: STX benefits from AI infrastructure tailwinds and earnings consistency, but high leverage and volatile cash flows present risks. The stock offers upside to analyst targets if execution continues, yet investors face sensitivity to memory market cycles and debt servicing challenges amid competitive pressures.
Trailing returns across standard periods
CRISPR Therapeutics is a gene editing company focused on the development of CRISPR/Cas9-based therapeutics. CRISPR/Cas9 stands for Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. The company is focused on using this technology to treat genetically defined diseases. CRISPR's most advanced pipeline candidate, CTX001, is in collaboration with Vertex Pharmaceuticals and targets sickle cell disease and transfusion-dependent beta-thalassemia, which have high unmet medical needs. The company is progressing additional gene editing programs for immuno-oncology, as well as a stem cell-derived therapy for the treatment of Type 1 diabetes.
Read more on CRSP →Seagate is a leading supplier of hard disk drives for data storage to the enterprise and consumer markets. It forms a practical duopoly in the market with its chief rival, Western Digital
Read more on STX →