Charles River Laboratories Intl. Inc vs Vanguard Total International Stock Index Fund ETF — how do they compare? Charles River Laboratories Intl. Inc trades at $232.53 (market cap $11.14B), while Vanguard Total International Stock Index Fund ETF trades at $85. Which is the better fit depends on your goals.
| CRL | VXUS | |
|---|---|---|
Market Cap | $11.14B | — |
Sector | Health | Sector/Thematic |
52-Week High | $233.60 | $87.06 |
52-Week Low | $145.57 | $68.24 |
Enterprise Value | $14.00B | — |
Signals from Pluang's Aura AI — not financial advice
Charles River Laboratories (CRL) trades at $229.75, down 1.57% on the day, near its consensus price target of $229.80. The stock shows a bullish technical trend with strong moving average signals and support at $225. Fundamentally, CRL has beaten EPS estimates for three consecutive quarters but reported a net loss of $144.34 million in 2025, with negative profit margins. Recent news highlights collaborations in AI and NGS services, supporting growth prospects.
Outlook remains mixed: analyst consensus is strongly bullish with 72% buy ratings and a high target of $260, but profitability challenges and high P/E of 684.85 pose risks. Cash flow stability and strategic partnerships offer upside, while margin pressures and debt levels require monitoring for sustained recovery.
VXUS trades at $83.78, down 1.83% amid bearish technical signals, with moving averages indicating selling pressure and key support at $83. The ETF offers broad international equity exposure across 8,738 stocks, though financial ratios are unavailable. Recent news highlights its role in diversification as U.S. valuations remain elevated.
Outlook hinges on global economic shifts; VXUS provides cost-effective diversification but faces headwinds from inflation and U.S. dominance. Risks include currency fluctuations and emerging market volatility, while analysts note its discount to U.S. peers could offer long-term value.
Trailing returns across standard periods
Latest headlines on both assets
Charles River Laboratories was founded in 1947 and is a leading provider of drug discovery and development services. The company's research model & services segment is the leading provider of animal models for laboratory testing, which breeds and delivers animal research models with specific genetic characteristics for preclinical studies around the world. The discovery & safety assessment segment includes services required to take a drug through the early development process, including discovery services. The manufacturing support segment includes microbial solutions, which provides in vitro (non-animal) testing products, biologics testing services, and avian vaccine services.
Read more on CRL →VXUS is a comprehensive, low-cost ETF that tracks the FTSE Global All Cap ex US Index, providing exposure to over 8,500 stocks in both developed and emerging markets outside the United States. It serves as a foundational building block for international diversification, allowing investors to own a market-cap-weighted slice of the entire non-U.S. investable equity universe in a single vehicle.
Read more on VXUS →