Charles River Laboratories Intl. Inc vs S&P500 ETF — how do they compare? Charles River Laboratories Intl. Inc trades at $227.69 (market cap $11.14B), while S&P500 ETF trades at $754.02. Which is the better fit depends on your goals.
| CRL | SPY | |
|---|---|---|
Market Cap | $11.14B | — |
Sector | Health | — |
52-Week High | $233.60 | $759.55 |
52-Week Low | $145.57 | $621.75 |
Enterprise Value | $14.00B | — |
Signals from Pluang's Aura AI — not financial advice
Charles River Laboratories (CRL) trades at $229.75, down 1.57% on the day, near its consensus price target of $229.80. The stock shows a bullish technical trend with strong moving average signals and support at $225. Fundamentally, CRL has beaten EPS estimates for three consecutive quarters but reported a net loss of $144.34 million in 2025, with negative profit margins. Recent news highlights collaborations in AI and NGS services, supporting growth prospects.
Outlook remains mixed: analyst consensus is strongly bullish with 72% buy ratings and a high target of $260, but profitability challenges and high P/E of 684.85 pose risks. Cash flow stability and strategic partnerships offer upside, while margin pressures and debt levels require monitoring for sustained recovery.
SPY trades at $749.08, down 0.77% on the day, with technical indicators showing a bullish bias from moving averages while oscillators remain neutral. The ETF approaches key resistance at $750 with support at $747. Recent news highlights analyst optimism with several firms projecting S&P 500 targets above 8,000 by year-end, though earnings season and inflation data remain key catalysts.
Outlook remains constructive given strong institutional sentiment and historical market performance, though risks include potential Fed policy shifts and valuation concerns. The dividend payment scheduled for July 31, 2026 provides income support, while technical consolidation near all-time highs suggests potential for breakout momentum if earnings deliver.
Trailing returns across standard periods
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Charles River Laboratories was founded in 1947 and is a leading provider of drug discovery and development services. The company's research model & services segment is the leading provider of animal models for laboratory testing, which breeds and delivers animal research models with specific genetic characteristics for preclinical studies around the world. The discovery & safety assessment segment includes services required to take a drug through the early development process, including discovery services. The manufacturing support segment includes microbial solutions, which provides in vitro (non-animal) testing products, biologics testing services, and avian vaccine services.
Read more on CRL →The ETF is designed to track the performance of the securities and the stocks in the S&P 500 Index. To maintain the composition and weightings, the advisor adjusts the ETF from time to time to conform to periodic changes in the index target.
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