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Compare Capital One Financial Corp. (COF) vs Crispr Therapeutics AG (CRSP) Price & Performance

Capital One Financial Corp.Trade
Crispr Therapeutics AGTrade

Price performance (Past 24H)

Key statistics

Capital One Financial Corp. vs Crispr Therapeutics AG — how do they compare? Capital One Financial Corp. trades at $209.41 (market cap $126.46B), while Crispr Therapeutics AG trades at $50.39 (market cap $4.97B). The key difference: Capital One Financial Corp. is far larger — about 25.4× Crispr Therapeutics AG's market cap, and Capital One Financial Corp. pays a 1.56% dividend while Crispr Therapeutics AG pays none. Which is the better fit depends on your goals.

COFCRSP
Market Cap
$126.46B$4.97B
Sector
FinancialsHealth
52-Week High
$257.94$76.78
52-Week Low
$176.10$44.34
Dividend Yield
1.56%
Enterprise Value
$3.32B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Capital One Financial Corp.

Capital One Financial (COF) trades at $203.02, up 0.74% with a bullish technical signal from moving averages. The stock shows mixed earnings performance with recent misses but strong revenue growth to $53.43B in 2025. Analyst consensus remains positive with a $252.40 price target and 62.5% buy ratings, while the Discover integration presents significant expansion opportunities amid credit risk concerns.

COF offers potential upside from current levels with Wall Street optimism around the Discover acquisition, though investors face headwinds from rising delinquencies and margin compression. The stock's valuation at 62.44 P/E appears elevated relative to modest ROE of 3.34%, requiring careful monitoring of integration execution and credit quality trends.

Crispr Therapeutics AG

CRSP trades at $50.63, down 5.1% over 24 hours, amid a bearish technical signal. The company shows deep losses with a net income margin of -56,853.4% in 2025 and negative cash flow from operations. However, analyst consensus remains optimistic with a $74.50 price target, and recent news highlights FDA approval for Casgevy, expanding its gene therapy market.

The outlook hinges on commercial execution of Casgevy and pipeline progress, offering high growth potential in gene editing. Key risks include sustained cash burn, competitive pressures, and regulatory hurdles. Despite current financial challenges, strong analyst buy ratings suggest confidence in long-term value.

Returns comparison

Trailing returns across standard periods

About Capital One Financial Corp.

Capital One is a diversified financial services holding company headquartered in McLean, Virginia. Originally a spinoff of Signet Financial's credit card division in 1994, the company is now primarily involved in credit card lending, auto loans, and commercial lending.

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About Crispr Therapeutics AG

CRISPR Therapeutics is a gene editing company focused on the development of CRISPR/Cas9-based therapeutics. CRISPR/Cas9 stands for Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. The company is focused on using this technology to treat genetically defined diseases. CRISPR's most advanced pipeline candidate, CTX001, is in collaboration with Vertex Pharmaceuticals and targets sickle cell disease and transfusion-dependent beta-thalassemia, which have high unmet medical needs. The company is progressing additional gene editing programs for immuno-oncology, as well as a stem cell-derived therapy for the treatment of Type 1 diabetes.

Read more on CRSP