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Compare Alnylam Pharmaceuticals, Inc. (ALNY) vs Upwork Inc (UPWK) Price & Performance

Alnylam Pharmaceuticals, Inc.Trade
Upwork IncTrade

Price performance (Past 24H)

Key statistics

Alnylam Pharmaceuticals, Inc. vs Upwork Inc — how do they compare? Alnylam Pharmaceuticals, Inc. trades at $222.01 (market cap $29.60B), while Upwork Inc trades at $8.47 (market cap $1.04B). The key difference: Alnylam Pharmaceuticals, Inc. is far larger — about 28.5× Upwork Inc's market cap. Which is the better fit depends on your goals.

ALNYUPWK
Market Cap
$29.60B$1.04B
Sector
HealthIndustrials
52-Week High
$491.22$22.11
52-Week Low
$205.48$7.84
Enterprise Value
$27.56B$806.15M

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Alnylam Pharmaceuticals, Inc.

ALNY trades at $223.43, up 2.97% in 24 hours, with a bearish technical signal despite recent gains. The stock shows strong profitability with a 79.65% gross margin and 96.55% ROE, but valuation ratios like P/E of 38.54 are elevated. Recent Q2 2026 earnings missed estimates, and multiple law firms are investigating potential securities fraud, adding uncertainty.

Outlook is mixed: analyst consensus is bullish with a $370.07 price target, but risks include ongoing fraud probes and earnings volatility. Revenue growth is robust, projected to reach $4.8B in 2026, yet investors face headwinds from legal issues and technical bearishness.

Upwork Inc

Upwork (UPWK) stock is trading at $8.385, down 14.7% on the day following Q2 2026 results. While the company beat earnings expectations with EPS of $0.41 versus $0.3424, weak forward guidance triggered the sell-off. The stock exhibits a bearish technical signal, trading near key support levels. Fundamentally, the company maintains solid profitability metrics, including a 77.21% gross margin and a P/E ratio of 10.71, but faces headwinds from declining active client counts and AI-related market shifts.

The outlook is cautious. Analyst consensus remains a 'Buy' with a $9.25 price target, suggesting potential upside from current levels. However, near-term risks are elevated due to the guidance miss, ongoing client attrition, and potential legal investigations. The stock's valuation appears reasonable, but investor confidence hinges on the company's ability to stabilize client growth and navigate the AI disruption in the freelance market.

Returns comparison

Trailing returns across standard periods

Top news

Latest headlines on both assets

About Alnylam Pharmaceuticals, Inc.

Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia.

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About Upwork Inc

Upwork Inc is a United States-based company that operates an online marketplace that enables businesses to find and work with highly-skilled independent professionals. The develops platform for hiring and freelancing purposes. Its products offering include Upwork Basic, Upwork Plus, Upwork Business, Upwork Enterprise, and Upwork Payroll. The business generates revenue from Talent and Clients across the USA, India, the Philippines and the rest of the world. Substantial income is derived from providing services to Clients.

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