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Zentalis reports 15.8-month median survival for ovarian cancer patients on azenosertib in DENALI study

Company Fundamentals
18 Oct 2026
GlobeNewsWire
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Bullish
Zentalis reports 15.8-month median survival for ovarian cancer patients on azenosertib in DENALI study

Zentalis Pharmaceuticals announced interim overall survival data from its DENALI Part 1b study showing a median survival of 15.8 months in Cyclin E1-positive platinum-resistant ovarian cancer patients treated with azenosertib monotherapy. This compares favorably to 7.5 months in Cyclin E1-negative patients and supports further development of azenosertib in this biomarker-selected group. The data will be presented at the ESMO Congress 2026, with ongoing Phase 2 and Phase 3 trials aiming for regulatory approval. No new safety concerns were reported, highlighting azenosertib's potential as a targeted oral treatment option for this hard-to-treat cancer subset.

Zentalis Pharmaceuticals' interim overall survival data for azenosertib in ovarian cancer highlights a median survival of 15.8 months in Cyclin E1-positive patients. For readers following the health sector, here is Pluang's market snapshot as of Oct 19, 2026 05:21 WIB: out of 150 priced US health stocks, 29 rose and 118 fell. Notable movers include DNA (Ginkgo Bioworks Holdings Inc) at USD 10.27 with a -12.67% change and a typical hold time of 8 days, NVAX (Novavax Inc) at USD 11.26 with a -12.17% change and a 59-day hold time, and SLS (SELLAS Life Sciences Group Inc.) at USD 9.98 with a -11.99% change and a 4-day hold time.

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