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Phase III trial of VQW-765 for social anxiety fails primary endpoint, program now on hold.

Market News
14 Oct 2026
PRNewsWire
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Bearish
Phase III trial of VQW-765 for social anxiety fails primary endpoint, program now on hold.

Vanda Pharmaceuticals announced that its Phase III clinical trial of VQW-765, aimed at treating acute social anxiety, did not meet its primary or key secondary endpoints. The study involved 546 adults and tested the drug's effect during a stress-inducing public speaking test but found no significant difference from placebo. Despite earlier promising Phase II results, the Phase III findings were negative, leading Vanda to pause the development program pending further data analysis. VQW-765 is a novel drug targeting the alpha 7 nicotinic acetylcholine receptor, with potential psychiatric applications but no current FDA approval for performance anxiety treatment.

Vanda Pharmaceuticals' update on its VQW-765 clinical development program is provided here with related market data. For readers following the health sector, 90 of 150 priced US health stocks on Pluang rose while 60 fell. Notable movers include CGC at USD 0.72 with a 5.60% decline and 98% sell order activity, CLPT at USD 9.30 down 5.20%, and WGS at USD 68.25 up 5.06% with 100% buy order activity. Data is as of Oct 15, 2026 03:02 WIB.

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