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HETLIOZ shows positive Phase III results for treating Delayed Sleep-Wake Phase Disorder, advancing sleep onset by 37 minutes.

Company Fundamentals
29 Sep 2026
PRNewsWire
View Source
Bullish
HETLIOZ shows positive Phase III results for treating Delayed Sleep-Wake Phase Disorder, advancing sleep onset by 37 minutes.

Vanda Pharmaceuticals announced that its Phase III study of HETLIOZ (tasimelteon) 20 mg met its primary endpoint by shifting sleep onset 37.1 minutes earlier in adults with Delayed Sleep-Wake Phase Disorder (DSWPD) compared to placebo. Sixty percent of treated participants advanced sleep onset by at least 30 minutes, versus 15% on placebo. Vanda plans to submit these data to the FDA seeking approval for HETLIOZ as the first treatment specifically for DSWPD, a disorder affecting millions with delayed internal body clocks. Safety results were consistent with previous uses of HETLIOZ, which is already approved for other circadian rhythm disorders.

Vanda Pharmaceuticals' positive Phase III results for HETLIOZ in Delayed Sleep-Wake Phase Disorder provide context alongside Pluang's Health-sector data. As of Sep 30, 2026 05:51 WIB, 43 of 100 Health-sector US stocks rose while 56 fell. Notably, DNA gained 15.77% with a typical hold time of 9 days, contrasting with WGS which dropped 11.82% and RXRX which rose 8.65% with a longer hold time of 23 days.

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