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Talphera hits 50% enrollment in NEPHRO CRRT study, closes $4.1M financing, eyes 2026 trial completion

Company Fundamentals
23 Mar 2026
PRNewsWire
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Bullish
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Talphera announced reaching 50% patient enrollment in its NEPHRO CRRT clinical study with all 12 sites active, supporting expected study completion in 2026. The company closed a $4.1 million financing tranche linked to this milestone and reported $20.4 million in cash and investments as of December 31, 2025. Operating expenses rose due to ongoing development and trial costs, with 2026 expenses forecasted at $17-18 million to finalize the study and prepare for FDA submission. Talphera also hosted a virtual investor day featuring principal investigators discussing the potential of nafamostat to address unmet needs in anticoagulation during CRRT.

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