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Coiled Therapeutics advances cancer drug trial with new reformulated AO-252 dosing progress

Market News
21 Sep 2026
Proactive Investors
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Bullish
Coiled Therapeutics advances cancer drug trial with new reformulated AO-252 dosing progress

Coiled Therapeutics has enrolled six patients in a trial testing a reformulated softgel version of its cancer drug AO-252, designed to improve absorption compared to the earlier tablet form. Shore Capital supports the progress and highlights the potential value of upcoming safety data expected by the end of 2026 and preliminary efficacy results in early 2027. The drug targets the TACC3 protein, which promotes tumor growth but is less critical to healthy cells, suggesting a chance for effective cancer treatment with fewer side effects. AO-252 has already demonstrated an 80% clinical benefit rate in a small group of heavily pre-treated patients, marking it as a promising candidate for further development and partnerships.

Coiled Therapeutics' cancer drug AO-252 trial progress is noted alongside Pluang's Health-sector market data. For readers following Health-sector stocks, here is Pluang's market snapshot as of Sep 21, 2026 20:01 WIB: Of 95 priced US Health-sector stocks, 56 rose and 25 fell. Notable movers include OSCR at USD 31.35 with a -2.43% change and a typical hold time of 14 days, ABEO at USD 5.46 with a -1.97% change and a 22-day hold time, and TXG at USD 78.08 with a +1.93% change and a 94-day hold time.

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