The FDA has granted accelerated approval to Sanofi's Tzield (teplizumab-mzwv) for children aged 8 to 17 recently diagnosed with stage 3 type 1 diabetes (T1D). This is the first disease-modifying therapy aimed at delaying the decline of insulin production in these patients, based on positive results from the PROTECT phase 3 study involving over 900 patients. Tzield targets the autoimmune attack on insulin-producing beta cells, potentially changing the treatment approach for stage 3 T1D. Continued approval depends on further confirmatory studies, with ongoing trials like BETA-PRESERVE underway.
A recent study by Spherix Global Insights highlights the unmet need for new treatments in warm autoimmune hemolytic anemia (w-AIHA), especially beyond second-line therapies where no clear standard exists. Current treatments rely heavily on corticoste...
Recludix Pharma announced preclinical results for REX-8756, an oral STAT6 inhibitor, showing strong efficacy and safety in models of allergic asthma and dermatitis. The data, presented at two major allergy and dermatology congresses, indicate that RE...
Sanofi has stopped its Phase 3 MOBILIZE trial testing riliprubart for chronic inflammatory demyelinating polyneuropathy (CIDP) due to unlikely efficacy success, though no safety issues were found. The company will review other riliprubart studies and...
Sanofi has stopped the phase 3 MOBILIZE clinical trial of riliprubart for treating chronic inflammatory demyelinating polyneuropathy (CIDP) after an interim review showed the study is unlikely to demonstrate sufficient efficacy. No safety concerns we...
HR Tech 2026, scheduled for October 20-22 in Las Vegas, announced its agenda centered on real-world AI implementation, workforce skills, and HR transformation. The event features sessions from leaders at major companies like IFF, Lumen, and Sanofi, c...
