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Denifanstat shows sustained acne improvement over 52 weeks in Phase 3 trial by Sagimet partner Ascletis.

Company Fundamentals
09 Oct 2026
GlobeNewsWire
View Source
Bullish
Denifanstat shows sustained acne improvement over 52 weeks in Phase 3 trial by Sagimet partner Ascletis.

Sagimet Biosciences' license partner Ascletis reported positive 52-week results from a Phase 3 open-label extension trial of denifanstat, an oral acne drug. The trial showed significant and sustained improvements in moderate to severe acne, including a 57% success rate on Investigator’s Global Assessment and substantial lesion reductions. Denifanstat, a fatty acid synthase inhibitor, targets acne by reducing sebum production and inflammation. Sagimet is advancing denifanstat into a U.S. Phase 3 trial, with patient screening underway.

Sagimet Biosciences' license partner Ascletis reported positive 52-week Phase 3 trial results for denifanstat in acne, providing context for health sector performance. For readers following the health sector, here is Pluang's market snapshot as of Oct 09, 2026 17:11 WIB: of 128 priced US health stocks, 66 rose and 52 fell. Notably, TXG traded at USD 79.00 with a 1-day change of +2.23% and a typical hold time of 92 days, contrasting with ACB at USD 4.34, down 2.03% with a 25-day hold time, and CNC at USD 65.76, up 1.89% with a 42-day hold time.

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