Rhythm Pharmaceuticals announced that its Phase 3 EMANATE trial of setmelanotide failed to meet the primary endpoint of BMI change at 52 weeks across four genetic cohorts. Despite this, post-hoc analyses revealed promising signals in POMC heterozygous and SRC1 subgroups, suggesting potential benefits in these populations. The trial faced challenges including high dropout rates and difficulties in variant classification. Rhythm will not seek regulatory approval based on these results and plans to focus on next-generation therapies and improved patient selection for future studies.
Purecore Metals Inc. has signed a non-binding letter of intent with Skyharbour Resources to acquire an option to earn up to 100% interest in the Yurchison uranium property in Saskatchewan's Athabasca Basin. The property covers over 35,000 hectares an...
Shirofune has introduced Walmart Connect, an integration that allows advertisers and agencies to manage Walmart retail media campaigns alongside other digital channels within a single platform. This automation reduces manual bid adjustments and repor...
Point completed a $508.6 million rated asset-backed securitization of its Home Equity Investment (HEI) assets, marking the largest transaction ever in the HEI asset class. The deal attracted over 30 institutional investors and priced at significantly...
The global reactive hot melt adhesives market is projected to grow from $2.02 billion in 2025 to $4.29 billion by 2035, at a CAGR of 7.72%. Growth is driven by regulations limiting solvent-based adhesives, increased use of polyurethane adhesives in a...
Red Light Holland, after acquiring Filament Health, has expanded its capabilities in pharmaceutical-grade psilocybin development. Filament completed a shipment of its botanical psilocybin drug candidate, PEX010, to the European Union to support multi...
