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Radiopharm advances 177Lu-RAD202 Phase 1 trial to higher dose for HER2+ tumors after positive safety review

Market News
08 Apr 2026
Na
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Bullish
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Radiopharm Theranostics received a positive recommendation from its Data Safety and Monitoring Committee to escalate the dose of its radiotherapeutic drug 177Lu-RAD202 to 130mCi in the ongoing Phase 1 HEAT trial targeting HER2-positive advanced solid tumors. This advancement reflects a favorable safety profile and allows the company to accelerate dose escalation, aiming to complete Phase 1 by the end of 2026. The trial is conducted across Australian clinical centers and builds on earlier positive safety and biodistribution results in HER2-positive breast cancer patients. This progress is significant as RAD202 targets a validated cancer marker, potentially offering new treatment options for patients with advanced solid tumors.

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