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GSK's hepatitis B drug Hibsago approved in US, boosting sales forecast to £2.2bn, but safety monitoring may slow uptake

Market News
21 Oct 2026
Proactive Investors
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Bullish
GSK's hepatitis B drug Hibsago approved in US, boosting sales forecast to £2.2bn, but safety monitoring may slow uptake

GSK's hepatitis B treatment, Hibsago (bepirovirsen), received FDA approval for adults with chronic hepatitis B without cirrhosis, supporting Jefferies' forecast of peak annual sales at £2.2 billion. The drug offers a potential functional cure, allowing some patients to stop long-term antiviral therapy, a significant advance over existing treatments. However, the treatment requires intensive safety monitoring due to risks like liver inflammation and low platelet counts, which could limit its commercial adoption. Jefferies highlights that the key challenge now is execution and market uptake, with potential for future combination therapies to expand patient benefits.

GSK shares are currently trading at USD 50.18 on Pluang, down 0.89% for the day, showing steady investor interest with 100% buy orders as of Oct 21, 2026 19:51 WIB. The stock maintains a dividend yield of 3.59%, reflecting ongoing value for shareholders amid the new drug approval news.

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