Researchers at Chonnam National University in South Korea have developed a new, efficient method for synthesizing amide bonds using dichloromethane, a common solvent, as a coupling reagent. This approach avoids toxic and wasteful reagents typically used in amide synthesis, making it more practical and environmentally friendly. The method works under basic conditions and has been successfully applied to produce pharmaceutical amides like procainamide and moclobemide with high yields. It also shows promise for large-scale production, offering a simpler and greener alternative for amide synthesis in medicine and materials chemistry.
The discovery by Chonnam University researchers of a century-old solvent for efficient amide synthesis provides context for basic materials market activity. For readers following the Basic Materials sector, here is Pluang's market snapshot as of Sep 25, 2026 18:31 WIB: of 38 priced US stocks, 24 rose and 13 fell. Notable movers include APD at USD 280.22 with a 1-day change of -1.50% and 70% sell order activity, AEM at USD 196.66 up 1.43% with 71% buy orders, and MT at USD 72.31 up 1.42% with 100% buy orders and a typical hold time of 35 days.
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