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ESR1-mutated metastatic breast cancer market to grow 9.6% CAGR with new oral SERDs and targeted therapies.

Market News
20 May 2026
Delveinsight
View Source
Bullish
pluang ai news

The ESR1-mutated metastatic breast cancer market is projected to grow rapidly at a 9.6% CAGR from 2026 to 2036, driven by rising cases of endocrine-resistant HR-positive/HER2-negative breast cancer and advances in precision oncology. Novel therapies like Giredestrant, Camizestrant, and VEPPANU, the first FDA-approved PROTAC therapy, are reshaping treatment options and expanding market opportunities. The US leads the market, with about 40% of advanced breast cancer patients developing ESR1 mutations during first-line therapy, which reduces treatment effectiveness. Emerging drugs are expected to transform the treatment landscape and improve patient outcomes in the coming decade.

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