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Monopar plans mid-2026 NDA submission for ALXN1840 to treat Wilson disease, reports Q4 and full-year 2025 results.

Company Fundamentals
27 Mar 2026
GlobeNewsWire
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Bullish
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Monopar Therapeutics announced its financial results for Q4 and full-year 2025, highlighting progress toward submitting a New Drug Application (NDA) for ALXN1840 in Wilson disease by mid-2026. ALXN1840, a novel treatment targeting copper accumulation in organs, showed promising long-term efficacy and safety data. The company strengthened its leadership and balance sheet in 2025, with $140.4 million in cash to support operations through 2027. Monopar also advanced its radiopharmaceutical programs targeting aggressive cancers, with ongoing Phase 1 trials and regulatory clearances. The NDA submission and potential launch of ALXN1840 mark key upcoming milestones.

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