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MannKind advances IPF treatment with Phase 1b randomization complete and Phase 2 trial started for inhaled nintedanib.

Company Fundamentals
03 Jun 2026
GlobeNewsWire
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Bullish
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MannKind Corporation has completed patient randomization in its Phase 1b INFLO-1 study and enrolled the first patient in the global Phase 2 INFLO-2 trial for nintedanib DPI, an inhaled therapy for idiopathic pulmonary fibrosis (IPF). The Phase 1b data, expected in Q3 2026, will assess safety and tolerability, while the Phase 2 study aims to evaluate efficacy and optimal dosing in about 210 patients worldwide. This inhaled form of nintedanib targets lung delivery to reduce systemic side effects compared to oral therapy, potentially improving patient adherence and enabling combination treatments. These milestones mark significant progress in developing a more convenient and potentially better-tolerated IPF treatment.

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