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Legend Biotech's LB2501 shows 100% response in Phase 1 trial for relapsed B-cell lymphoma with good safety.

Company Fundamentals
14 Jun 2026
GlobeNewsWire
View Source
Bullish
pluang ai news

Legend Biotech announced that its investigational CAR-T therapy LB2501 achieved a 100% objective response rate and 83.3% complete response rate at the higher dose in a Phase 1 trial for relapsed or refractory B-cell non-Hodgkin lymphoma. The single infusion treatment generated CAR-T cells in vivo without lymphodepletion and showed a favorable safety profile, with no serious adverse events or deaths reported. These promising early results support further development of LB2501 as a novel, simplified CAR-T therapy that could improve treatment access for patients with limited options.

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