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Miv-cel shows sustained clinical benefits in stiff person syndrome after one year in registrational trial

Company Fundamentals
21 Oct 2026
GlobeNewsWire
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Bullish
Miv-cel shows sustained clinical benefits in stiff person syndrome after one year in registrational trial

Kyverna Therapeutics announced one-year data from its KYSA-8 trial showing that miv-cel, a CAR T-cell therapy, significantly improves mobility and reduces disability in patients with stiff person syndrome (SPS). The single-dose treatment demonstrated durable efficacy across multiple measures, with most patients remaining off chronic immunotherapies and experiencing improved physical and mental health. The therapy showed a favorable safety profile with no severe side effects like high-grade CRS or ICANS. These results support miv-cel's potential as the first approved treatment for SPS and a breakthrough CAR T-cell therapy for autoimmune diseases.

Kyverna Therapeutics data on miv-cel in stiff person syndrome offers context for health sector investors. For readers following health stocks, here is Pluang's market snapshot as of Oct 21, 2026 18:11 WIB: 71 of 150 health-sector US stocks rose, 67 fell. Notable movers include TWST at USD 137.09 with 0% sell and 100% buy activity, TNGX at USD 26.20 up 3.76%, and BAX at USD 25.30 up 3.22%.

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