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Safety committee approves higher 18 mg/kg dose for Entrada's Duchenne muscular dystrophy drug trial

Market News
14 Oct 2026
GlobeNewsWire
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Bullish
Safety committee approves higher 18 mg/kg dose for Entrada's Duchenne muscular dystrophy drug trial

Entrada Therapeutics announced that an independent Data Monitoring Committee has recommended advancing to Cohort 3 at the top dose of 18 mg/kg in their Phase 1/2 ELEVATE-44-201 clinical trial for ENTR-601-44, a potential treatment for Duchenne muscular dystrophy (DMD). This follows positive safety and pharmacokinetic data from Cohort 2, which used a 12 mg/kg dose. The higher dose aims to increase drug exposure and dystrophin production, potentially improving patient outcomes. Data from Cohort 1's open-label period is expected by the end of 2026, with Cohort 2 results due in early 2027, marking important steps in the drug's development.

Entrada Therapeutics' clinical trial update comes as the Health sector on Pluang shows broad gains, with 103 of 150 US stocks rising as of Oct 14, 2026 18:11 WIB. Notable movers include Liquidia Corporation (LQDA) up 52.74% to USD 40.95, Abeona Therapeutics (ABEO) up 10.62% to USD 5.00 with a typical hold time of 26 days, and Brookdale Senior Living (BKD) up 7.41% to USD 10.87. This snapshot reflects active trading and positive momentum in the Health sector on Pluang's platform.

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