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Paxalisib trial for rare epilepsy starts, triggering $2M payment to Kazia Therapeutics

Company Fundamentals
22 Sep 2026
PRNewsWire
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Bullish
Paxalisib trial for rare epilepsy starts, triggering $2M payment to Kazia Therapeutics

Kazia Therapeutics received a $2 million milestone payment as Sovargen dosed the first patient in a Phase 1b/2a trial of paxalisib for treating rare epilepsies linked to mTOR pathway disorders, including focal cortical dysplasia type 2 and tuberous sclerosis complex. This trial marks a significant expansion of paxalisib's development beyond cancer, targeting neurological diseases with unmet treatment needs. Sovargen holds exclusive rights outside China and is responsible for further development and commercialization, with Kazia eligible for up to $17 million more in milestones plus royalties. The study's progress could open new therapeutic avenues for patients with drug-resistant seizures.

Kazia Therapeutics' news on Sovargen dosing the first patient in a Phase 1b/2a trial is presented with Pluang's Health sector data for context. Among 95 priced US health stocks on Pluang as of Sep 22, 2026 18:11 WIB, 50 advanced while 38 declined. Notably, ADPT traded at USD 27.01 with a 3.05% drop and full buy-side order activity, contrasting with CTXR's USD 0.59 price and 2.91% gain alongside 97% buy orders, while ABEO fell 1.76% to USD 5.57.

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