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Karyopharm beats Q2 revenue estimates but reports larger EPS loss, focusing on oncology programs.

Company Fundamentals
13 Aug 2026
Andrew Wynn
View Source
Neutral
Karyopharm beats Q2 revenue estimates but reports larger EPS loss, focusing on oncology programs.

Karyopharm Therapeutics reported Q2 revenue of $33.43 million, beating estimates thanks to strong sales of its cancer drug XPOVIO®. However, the company missed EPS expectations with a loss of $2.32 per share and faces financial challenges including negative debt-to-equity and cash flow ratios. Karyopharm is shifting focus to its Myelofibrosis program and advancing its Selinexor drug, maintaining its full-year revenue guidance of $130-$150 million.

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