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Johnson & Johnson unveils new Phase 3 data for CAPLYTA in bipolar mania and updates on SPRAVATO and other neuropsychiatric treatments

Market News
08 Sep 2026
PRNewsWire
View Source
Bullish
Johnson & Johnson unveils new Phase 3 data for CAPLYTA in bipolar mania and updates on SPRAVATO and other neuropsychiatric treatments

Johnson & Johnson announced new pivotal Phase 3 clinical data for CAPLYTA (lumateperone) in treating bipolar mania, alongside additional findings in bipolar depression and major depressive disorder. The data, presented at the 2026 Psych Congress, highlight CAPLYTA's potential across mood disorders. The company also shared new analyses on SPRAVATO (esketamine) nasal spray for depression symptoms like anhedonia, and real-world evidence on long-acting injectables for schizophrenia and seltorexant for depression with insomnia. These updates underscore J&J's commitment to advancing treatments for complex neuropsychiatric conditions where patients face significant challenges.

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