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TREMFYA shows consistent remission in Crohn's disease with perianal fistula across key patient groups in Phase 3 trial

Company Fundamentals
12 Oct 2026
PRNewsWire
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Bullish
TREMFYA shows consistent remission in Crohn's disease with perianal fistula across key patient groups in Phase 3 trial

Johnson & Johnson's TREMFYA (guselkumab) demonstrated consistent combined fistula remission rates of up to 28% at Week 24 in adults with Crohn's disease and perianal fistula, outperforming placebo at 10%. New Phase 3 subgroup analyses from the FUZION study showed efficacy across patients with prior biologic exposure, varying disease activity, and presence or absence of proctitis. This marks the first positive dedicated randomized trial in over 20 years for this difficult-to-treat condition, addressing a significant unmet medical need. TREMFYA's safety profile remained consistent with previous findings, supporting its potential as a treatment option for complex Crohn's disease cases.

Johnson & Johnson's stock price on Pluang is USD 264.37 as of Oct 13, 2026, 03:02 WIB, showing a 1.12% increase in one day. The company holds a substantial market cap of $630.04 billion, reflecting its significant presence in the health sector. Despite the positive clinical trial news, the majority of Pluang users are selling JNJ shares, with 84% of order activity being sell orders at this time.

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