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GNS561 shows safety and early anti-tumor activity in Phase 1b trial for advanced cholangiocarcinoma patients.

Company Fundamentals
23 Jun 2026
Genfit
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Bullish
pluang ai news

GENFIT announced positive Phase 1b results for its experimental drug GNS561 combined with a MEK inhibitor in heavily pretreated patients with advanced cholangiocarcinoma (CCA) harboring KRAS mutations. The drug demonstrated a favorable safety and tolerability profile with no dose-limiting toxicities and showed early signs of anti-tumor activity, including disease stabilization in about half of the patients at 6 weeks. Based on these findings, GENFIT plans to expand the Phase 1b study with higher doses and proceed to Phase 2 in the second half of 2026, aiming to address the high unmet medical need in this aggressive cancer with limited treatment options.

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Shirofune launches Walmart Connect to automate and unify retail media campaign management.

Shirofune launches Walmart Connect to automate and unify retail media campaign management.

Shirofune has introduced Walmart Connect, an integration that allows advertisers and agencies to manage Walmart retail media campaigns alongside other digital channels within a single platform. This automation reduces manual bid adjustments and repor...

Market News
Bullish
49 minutes ago
Purecore signs LOI to option 100% of Yurchison uranium property in Canada's Athabasca Basin

Purecore signs LOI to option 100% of Yurchison uranium property in Canada's Athabasca Basin

Purecore Metals Inc. has signed a non-binding letter of intent with Skyharbour Resources to acquire an option to earn up to 100% interest in the Yurchison uranium property in Saskatchewan's Athabasca Basin. The property covers over 35,000 hectares an...

Company Fundamentals
Bullish
49 minutes ago
Point closes $508.6M HEI securitization, largest ever in home equity investment class

Point closes $508.6M HEI securitization, largest ever in home equity investment class

Point completed a $508.6 million rated asset-backed securitization of its Home Equity Investment (HEI) assets, marking the largest transaction ever in the HEI asset class. The deal attracted over 30 institutional investors and priced at significantly...

Company Fundamentals
Bullish
49 minutes ago
Reactive hot melt adhesives market to reach $4.29B by 2035, driven by automotive and furniture demand.

Reactive hot melt adhesives market to reach $4.29B by 2035, driven by automotive and furniture demand.

The global reactive hot melt adhesives market is projected to grow from $2.02 billion in 2025 to $4.29 billion by 2035, at a CAGR of 7.72%. Growth is driven by regulations limiting solvent-based adhesives, increased use of polyurethane adhesives in a...

Market News
Bullish
1 hour ago
Cardano smart contracts can now verify thousands of signatures on-chain cheaply using BLS12-381.

Cardano smart contracts can now verify thousands of signatures on-chain cheaply using BLS12-381.

Cardano has introduced native support for BLS12-381 elliptic curve cryptography in its Plutus smart contracts, enabling the verification of thousands of signatures on-chain at a low and predictable cost. This technology compresses multiple signatures...

Protocol Fundamentals
Bullish
4 hours ago
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