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FDA approves Jaypirca for first-line treatment of untreated chronic lymphocytic leukemia without 17p deletion

Market News
02 Oct 2026
PRNewsWire
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Bullish
FDA approves Jaypirca for first-line treatment of untreated chronic lymphocytic leukemia without 17p deletion

The FDA has approved Eli Lilly's Jaypirca (pirtobrutinib) for use as a first-line treatment in adult patients with previously untreated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) without the 17p deletion. This approval is based on the Phase 3 BRUIN CLL-313 trial, which showed Jaypirca significantly delays disease progression compared to chemoimmunotherapy, with a favorable safety profile. Jaypirca is the first non-covalent BTK inhibitor approved for this use, offering a new targeted therapy option for patients. Lilly continues to study Jaypirca in multiple ongoing Phase 3 trials to further define its role in CLL/SLL treatment.

Following the FDA's expanded approval of Lilly's Jaypirca for certain leukemia patients, Eli Lilly And Co shares are trading slightly lower on Pluang. As of Oct 03, 2026 02:21 WIB, LLY is priced at USD 1,145.85, down 0.48% for the day. The stock holds a market cap of $1.02 trillion and a dividend yield of 0.6%, with typical investor hold time around 93 days.

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