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EyePoint shares plunge after DURAVYU fails Phase 3 trial for wet AMD, prompting major workforce cuts.

Market News
19 Oct 2026
Gordon Thompson
View Source
Bearish
EyePoint shares plunge after DURAVYU fails Phase 3 trial for wet AMD, prompting major workforce cuts.

EyePoint's stock dropped sharply after its DURAVYU treatment did not meet the primary endpoint in a Phase 3 trial for wet age-related macular degeneration (wet AMD). Although DURAVYU showed some vision improvement and reduced the need for additional treatments by 38%, it failed to prove non-inferiority to the comparator drug aflibercept. In response, EyePoint is halting its wet AMD trials early, cutting its workforce by 53%, and shifting focus to DURAVYU's development for diabetic macular edema, with Phase 3 results expected in late 2027. Citigroup lowered its price target from $17 to $4 but maintained a Buy rating.

EyePoint's recent trial results provide context for health-sector market activity on Pluang. For readers following health stocks, here is Pluang's market snapshot as of Oct 19, 2026 22:21 WIB: Among 150 priced health-sector US stocks, 73 rose and 70 fell today. Notable movers include MESO (Mesoblast Limited) at USD 12.00 with a -9.64% change and a typical hold time of 16 days, IBRX (ImmunityBio Inc. Common Stock) at USD 8.51 down 7.35% with a 3-day hold, and SMMT (Summit Therapeutics Inc) at USD 15.68 up 7.18% with a 17-day hold time.

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