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Enliven to start Phase 3 ENABLE-2 trial for relcobatinib in chronic myeloid leukemia by end of 2026

Market News
06 Oct 2026
PRNewsWire
View Source
Bullish
Enliven to start Phase 3 ENABLE-2 trial for relcobatinib in chronic myeloid leukemia by end of 2026

Enliven Therapeutics has finalized the design of its ENABLE-2 Phase 3 trial for relcobatinib, a drug targeting chronic myeloid leukemia (CML). The trial will compare relcobatinib to second-generation treatments in about 450 patients previously treated with tyrosine kinase inhibitors. The primary goal is to improve major molecular response rates at 24 weeks, aiming for at least a 10% improvement over current therapies. Enliven plans to begin the trial before the end of 2026, moving closer to potentially offering a best-in-class treatment for CML.

Enliven Therapeutics' recent FDA alignment on its ENABLE-2 Phase 3 trial design for relcobatinib provides context for healthcare sector activity. For readers following health stocks, here is Pluang's market snapshot as of Oct 07, 2026 03:04 WIB: out of 100 priced US health-sector stocks, 47 rose and 53 fell. Notable movers include MESO at USD 13.58 with a 1-day change of -4.50% and a typical hold time of 14 days, CLPT at USD 11.01 down 4.43% with 79% buy order activity and a 9-day hold, and HUM at USD 404.74 up 4.22% with a typical hold time of 53 days but 100% sell order activity.

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