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New Phase 3 study shows TALVEY plus daratumumab boosts survival in relapsed multiple myeloma patients.

Company Fundamentals
13 Jun 2026
Johnson & Johnson
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Bullish
New Phase 3 study shows TALVEY plus daratumumab boosts survival in relapsed multiple myeloma patients.

Johnson & Johnson announced that the Phase 3 MonumenTAL-3 study demonstrated that TALVEY (talquetamab) combined with daratumumab, with or without pomalidomide, significantly improved progression-free survival (up to 81.3%) and overall survival (up to 89.2%) at 24 months in patients with relapsed or refractory multiple myeloma. The study showed a 72% reduction in disease progression or death risk compared to standard treatment. These results mark the first Phase 3 evidence of a GPRC5D bispecific antibody combination's effectiveness earlier in treatment, potentially expanding therapeutic options. Johnson & Johnson is pursuing regulatory approvals to bring this combination to patients globally.

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