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Biohaven licenses MoDE IgG degraders to Ono for Japan, South Korea, Taiwan, and ASEAN with $100M upfront plus royalties

Company Fundamentals
08 Oct 2026
PRNewsWire
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Bullish
Biohaven licenses MoDE IgG degraders to Ono for Japan, South Korea, Taiwan, and ASEAN with $100M upfront plus royalties

Biohaven has granted Ono Pharmaceutical an exclusive license to develop and commercialize its MoDE pan IgG degrader portfolio, including the lead drug BHV-1300, in Japan, South Korea, Taiwan, and ASEAN countries. Biohaven will receive up to $100 million in near-term payments, including $80 million upfront and $20 million upon a milestone, plus about 20% royalties on net sales. BHV-1300 is in Phase 3 trials for Graves' disease and has shown promising results in reducing disease-causing antibodies and normalizing thyroid hormones. This collaboration leverages Biohaven's innovative Yale-originated MoDE platform and Ono's regional development and commercial expertise, marking a significant step for extracellular protein degrader therapies in Asia.

Biohaven's strategic licensing deal with Ono Pharma for IgG degraders provides context for health-sector trading on Pluang. As of Oct 08, 2026 15:02 WIB, 34 of 100 health stocks rose while 59 fell. Among notable movers, Novavax Inc (NVAX) traded at USD 11.09 with 79% sell orders and a typical hold time of 59 days, contrasting with Twist Bioscience Corp (TWST) at USD 154.01, which saw 97% buy orders and a shorter hold time of 27 days. Koninklijke Philips NV (PHG) had 100% buy orders at USD 23.84 and a longer hold time of 84 days, illustrating varied investor engagement across health stocks on Pluang.

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