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APR-1051 shows promising anti-tumor activity with confirmed partial response in Phase 1 trial for biomarker-defined cancers

Company Fundamentals
30 Mar 2026
GlobeNewsWire
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Bullish
pluang ai news

Aprea Therapeutics announced a confirmed partial response in its Phase 1 ACESOT-1051 trial of APR-1051, a WEE1 kinase inhibitor, in a patient with PPP2R1A-mutated endometrial cancer. The patient showed a 59.5% reduction in tumor size and significant biomarker improvement, indicating sustained anti-tumor activity. APR-1051 has been generally well tolerated with mild side effects, supporting its potential as a best-in-class therapy for genetically defined cancers. Dose escalation and patient enrollment continue, with further trial updates expected in Q2 2026.

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Shirofune launches Walmart Connect to automate and unify retail media campaign management.

Shirofune launches Walmart Connect to automate and unify retail media campaign management.

Shirofune has introduced Walmart Connect, an integration that allows advertisers and agencies to manage Walmart retail media campaigns alongside other digital channels within a single platform. This automation reduces manual bid adjustments and repor...

Market News
Bullish
40 minutes ago
Purecore signs LOI to option 100% of Yurchison uranium property in Canada's Athabasca Basin

Purecore signs LOI to option 100% of Yurchison uranium property in Canada's Athabasca Basin

Purecore Metals Inc. has signed a non-binding letter of intent with Skyharbour Resources to acquire an option to earn up to 100% interest in the Yurchison uranium property in Saskatchewan's Athabasca Basin. The property covers over 35,000 hectares an...

Company Fundamentals
Bullish
40 minutes ago
Point closes $508.6M HEI securitization, largest ever in home equity investment class

Point closes $508.6M HEI securitization, largest ever in home equity investment class

Point completed a $508.6 million rated asset-backed securitization of its Home Equity Investment (HEI) assets, marking the largest transaction ever in the HEI asset class. The deal attracted over 30 institutional investors and priced at significantly...

Company Fundamentals
Bullish
40 minutes ago
Reactive hot melt adhesives market to reach $4.29B by 2035, driven by automotive and furniture demand.

Reactive hot melt adhesives market to reach $4.29B by 2035, driven by automotive and furniture demand.

The global reactive hot melt adhesives market is projected to grow from $2.02 billion in 2025 to $4.29 billion by 2035, at a CAGR of 7.72%. Growth is driven by regulations limiting solvent-based adhesives, increased use of polyurethane adhesives in a...

Market News
Bullish
1 hour ago
$1.7B invested to deploy Bloom Energy fuel cells powering AI cloud infrastructure for Nebius.

$1.7B invested to deploy Bloom Energy fuel cells powering AI cloud infrastructure for Nebius.

Industrial Development Funding (IDF) and Oaktree have committed $1.7 billion to support Bloom Energy's fuel cell technology for building AI cloud infrastructure for Nebius. This project will provide dedicated behind-the-meter power to meet the high c...

Market News
Bullish
4 hours ago
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