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AN2 Therapeutics rated speculative buy despite drug failure, eyeing new use for polycythemia vera treatment.

Analyst Insights
22 Sep 2026
Seeking Alpha
View Source
Bullish
AN2 Therapeutics rated speculative buy despite drug failure, eyeing new use for polycythemia vera treatment.

AN2 Therapeutics is rated a speculative buy with a valuation target of about $12 per share, compared to its recent price of $5.05. The company’s drug epetraborole failed as a treatment for refractory MAC lung disease but shows promise for treating polycythemia vera by reducing red blood cell parameters in a dose-dependent and reversible way. Early human and primate data support this potential, but further trials must prove it can control hematocrit and reduce the need for phlebotomy without causing serious anemia. Risks include prior drug efficacy issues, licensing obligations, uncertain patent protection, and possible dilution, though additional programs targeting M. abscessus and Chagas disease offer extra opportunities.

AN2 Therapeutics and its drug development are the subject, with Pluang's health sector data providing market context. Of 101 priced health-sector US stocks on Pluang, 54 rose and 41 fell today. Notable movers include FLNA at USD 0.93 with a 25.90% increase and WGS at USD 91.15 with a 6.83% decrease, as of Sep 22, 2026 20:31 WIB.

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