Adial Pharmaceuticals has named Dr. David Rubenstein as Chief Scientist to lead the development of AT177, an oral, colon-targeted AhR agonist for ulcerative colitis. Dr. Rubenstein brings experience from Dermavant Sciences, where he led the development of tapinarof, the first FDA-approved AhR agonist. AT177 aims to activate the AhR receptor locally in the colon with minimal systemic exposure, potentially offering a new treatment for ulcerative colitis. The drug is currently in IND-enabling studies, with clinical trials planned for 2027.
Adial Pharmaceuticals' recent appointment of Dr. David Rubenstein as Chief Scientist comes alongside a broadly positive day in the health sector on Pluang, with 95 of 150 priced US health stocks rising as of Oct 16, 2026 18:11 WIB. For readers following health stocks, here is Pluang's market snapshot: Amneal Pharmaceuticals Inc. (AMRX) traded at USD 19.50 with a 1-day change of +1.30% and a typical hold time of 7 days; Canopy Growth Corp (CGC) was priced at USD 0.74, up 1.29%, with Pluang order activity showing 100% sell; and Nuwellis Inc (NUWE) stood at USD 0.56, up 1.23%, with a near-even sell/buy split and a typical hold time of 27 days.
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