AstraZeneca plc vs Hewlett Packard Enterprise Co — how do they compare? AstraZeneca plc trades at $168.37 (market cap $253.13B), while Hewlett Packard Enterprise Co trades at $47.02 (market cap $65.63B). The key difference: AstraZeneca plc is far larger — about 3.9× Hewlett Packard Enterprise Co's market cap, and AstraZeneca plc pays the higher dividend (1.92%). Which is the better fit depends on your goals.
| AZN | HPE | |
|---|---|---|
Market Cap | $253.13B | $65.63B |
Sector | Health | Technology |
52-Week High | $209.48 | $56.14 |
52-Week Low | $137.44 | $19.81 |
Enterprise Value | $279.37B | $81.58B |
Dividend Yield | 1.92% | 1.15% |
Signals from Pluang's Aura AI — not financial advice
AstraZeneca (AZN) trades at $169.47, down 1.25% amid recent volatility following a Phase III trial failure for Wainua. The stock shows bearish technical signals with key support at $168 and resistance at $170. Fundamentally, the company reported strong 2025 results with revenue of $58.74B and net income of $10.23B, though a recent $1.5B licensing deal for a lung cancer drug highlights ongoing pipeline investments. Analyst sentiment is mixed with 47.5% buy ratings but recent downgrades from firms like HSBC citing trial setbacks.
The outlook balances robust financials against pipeline execution risks. Revenue growth and high margins support valuation, but the Wainua failure raises concerns about future catalysts. Investors should weigh the company's strong cash flow and market position against clinical trial volatility and potential legal investigations. Near-term price action may hinge on Q2 2026 earnings due July 27, 2026.
HPE trades at $47.24, down 2.61% on the day, with a bullish technical signal from moving averages. Recent earnings beats and a consensus price target of $69.69 suggest upside potential. The company reported revenue of $34.30B in 2025, though net income fell sharply to $57M. Strong AI infrastructure demand and a nearly $6B backlog, as noted by The Motley Fool on July 9, 2026, highlight growth catalysts.
Outlook is positive with AI-driven demand boosting revenue projections to $38.8B in 2026. Risks include high debt-to-asset ratio of 29.48% in 2025 and margin pressures. Analysts are mixed with 46% buy ratings, indicating cautious optimism for long-term investors amid near-term volatility.
Trailing returns across standard periods
Latest headlines on both assets
A merger between Astra of Sweden and Zeneca Group of the United Kingdom formed AstraZeneca in 1999. The firm sells branded drugs across several major therapeutic classes, including gastrointestinal, diabetes, cardiovascular, respiratory, cancer, and immunology. The majority of sales come from international markets with the United States representing close to one third of its sales.
Read more on AZN →Hewlett Packard Enterprise is an information technology vendor that provides hardware and software to enterprises. Its primary product lines are compute servers, storage arrays, and networking equipment.
Read more on HPE →