AstraZeneca plc vs Home Depot Inc — how do they compare? AstraZeneca plc trades at $167 (market cap $253.13B), while Home Depot Inc trades at $337.99 (market cap $336.77B). The key difference: Home Depot Inc is the larger of the two by market cap, and Home Depot Inc pays the higher dividend (2.76%). Which is the better fit depends on your goals.
| AZN | HD | |
|---|---|---|
Market Cap | $253.13B | $336.77B |
Sector | Health | Consumer Cyclical |
52-Week High | $209.48 | $423.42 |
52-Week Low | $137.44 | $297.51 |
Enterprise Value | $279.37B | $398.32B |
Dividend Yield | 1.92% | 2.76% |
Signals from Pluang's Aura AI — not financial advice
AstraZeneca (AZN) trades at $169.47, down 1.25% amid recent volatility following a Phase III trial failure for Wainua. The stock shows bearish technical signals with key support at $168 and resistance at $170. Fundamentally, the company reported strong 2025 results with revenue of $58.74B and net income of $10.23B, though a recent $1.5B licensing deal for a lung cancer drug highlights ongoing pipeline investments. Analyst sentiment is mixed with 47.5% buy ratings but recent downgrades from firms like HSBC citing trial setbacks.
The outlook balances robust financials against pipeline execution risks. Revenue growth and high margins support valuation, but the Wainua failure raises concerns about future catalysts. Investors should weigh the company's strong cash flow and market position against clinical trial volatility and potential legal investigations. Near-term price action may hinge on Q2 2026 earnings due July 27, 2026.
Home Depot (HD) trades at $337.11, down 1.8% on the day, with technical indicators showing bearish momentum as the stock tests key support levels. The company maintains strong fundamentals with $159.51B in revenue and 8.41% net margins, though recent earnings showed mixed results with a Q3 2025 miss followed by beats in subsequent quarters. Analyst consensus remains bullish with a $370.59 price target, while institutional activity shows mixed positioning amid housing market headwinds.
HD presents a compelling long-term investment case with solid profitability and market leadership, though near-term challenges include weakening big-ticket demand and margin pressure from investments. The stock's current discount to analyst targets offers potential upside, but investors should monitor housing market trends and consumer spending patterns that could impact performance.
Trailing returns across standard periods
Latest headlines on both assets
A merger between Astra of Sweden and Zeneca Group of the United Kingdom formed AstraZeneca in 1999. The firm sells branded drugs across several major therapeutic classes, including gastrointestinal, diabetes, cardiovascular, respiratory, cancer, and immunology. The majority of sales come from international markets with the United States representing close to one third of its sales.
Read more on AZN →Home Depot is the world's largest home improvement specialty retailer, operating more than 2,300 warehouse-format stores offering more than 30,000 products in store and 1 million products online in the United States, Canada, and Mexico. Its stores offer numerous building materials, home improvement products, lawn and garden products, and decor products and provide various services, including home improvement installation services and tool and equipment rentals. The acquisition of distributor Interline Brands in 2015 allowed Home Depot to enter the maintenance, repair, and operations business, which has been expanded through the tie-up with HD Supply (2020). The addition of the Company Store brought textile exposure to Home Depot's lineup.
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