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Compare Axogen Inc (AXGN) vs 22nd Century Group Inc (XXII) Price & Performance

Axogen IncTrade
22nd Century Group IncTrade

Price performance (Past 24H)

Key statistics

Axogen Inc vs 22nd Century Group Inc — how do they compare? Axogen Inc trades at $49.66 (market cap $2.61B), while 22nd Century Group Inc trades at $4.21 (market cap $1.52M). The key difference: Axogen Inc is far larger — about 1717.1× 22nd Century Group Inc's market cap, and Axogen Inc is trading nearer its 52-week high, 22nd Century Group Inc nearer its low. Which is the better fit depends on your goals.

AXGNXXII
Market Cap
$2.61B$1.52M
Sector
TechnologyTechnology
52-Week High
$48.48$801.00
52-Week Low
$14.16$3.72
Enterprise Value
$2.52B-$6.71M

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Axogen Inc

AXGN trades at $49.67, up 3.01% with strong technical momentum. The stock shows bullish moving average signals despite recent earnings misses. Q2 2026 revenue grew 23.1% to $69.7M with raised full-year guidance to $279M, though net margins remain negative at -13.36%. Analyst consensus is strongly bullish with 16 buy ratings and $54.33 price target.

Growth prospects appear strong with expanding nerve care platform and reimbursement wins, but profitability challenges and high valuation multiples present risks. The stock trades near resistance at $50 with RSI indicating overbought conditions, suggesting potential near-term consolidation before further upside.

22nd Century Group Inc

22nd Century Group (XXII) trades at $4.31, down 0.92% on the day, with a neutral technical signal and bearish moving averages. The company shows deep unprofitability with a gross margin of -52.19% and net margin of -65.76%, though revenue was $7.05M in 2025. Recent corporate actions include a 20:1 reverse stock split in June 2026, and news highlights retail expansion for VLN reduced-nicotine cigarettes in California and New York.

The outlook remains speculative with high execution risk amid persistent losses, but analyst sentiment is bullish with 75% buy ratings. Key risks include negative cash flow from operations, regulatory hurdles for tobacco products, and the need for successful commercialization of VLN to achieve profitability.

Returns comparison

Trailing returns across standard periods

About Axogen Inc

Axogen is a leader in peripheral nerve regeneration and repair. It provides innovative surgical solutions and clinically proven products, like nerve grafts, to help restore function and quality of life for patients.

Read more on AXGN

About 22nd Century Group Inc

22nd Century Group is a plant biotechnology company that uses genetic engineering and gene editing to control the levels of nicotine in tobacco plants. Its flagship product line, VLN®, is the first and only combustible cigarette authorized by the FDA as a Modified Risk Tobacco Product (MRTP), containing 95% less nicotine than traditional cigarettes to help adult smokers smoke less.

Read more on XXII