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Compare AST SpaceMobile Inc (ASTS) vs Twist Bioscience Corp (TWST) Price & Performance

AST SpaceMobile Inc
Twist Bioscience Corp

Price performance

Price movement over the last 24 hours

Key statistics

AST SpaceMobile Inc vs Twist Bioscience Corp — how do they compare? AST SpaceMobile Inc trades at $72.23 (market cap $21.90B), while Twist Bioscience Corp trades at $90.35 (market cap $5.64B). The key difference: AST SpaceMobile Inc is far larger — about 3.9× Twist Bioscience Corp's market cap, and Twist Bioscience Corp is trading nearer its 52-week high, AST SpaceMobile Inc nearer its low. Which is the better fit depends on your goals.

ASTSTWST
Market Cap
$21.90B$5.64B
Sector
MediaHealth
52-Week High
$133.09$102.88
52-Week Low
$36.91$24.16
Enterprise Value
$21.87B$5.57B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

AST SpaceMobile Inc

ASTS trades at $73.32, down 0.76% on the day, with a bearish technical signal from moving averages and mixed oscillators. The company reported revenue of $70.92 million in 2025 but sustained a net loss of $341.94 million, missing earnings expectations for three consecutive quarters. Recent news highlights potential in defense communications via satellite technology, though competition with SpaceX remains a focal point.

The outlook is speculative with high execution risk; analyst consensus is divided with a $90.33 price target. Investment opportunity hinges on successful satellite deployment and partnership execution, but persistent losses and intense competition pose significant downside risks for shareholders.

Twist Bioscience Corp

Twist Bioscience (TWST) trades at $90.64, down 3.24% today, with a bullish technical signal from moving averages and ADX indicators. The company shows strong revenue growth from $204M in 2022 to $377M in 2025, though it remains unprofitable with a net income margin of -19.85%. Recent developments include AI-driven drug discovery collaborations and expansion of clonal genes offerings, positioning TWST in the growing synthetic biology market.

While analyst consensus is strongly bullish (77% buy ratings) with a $87.88 price target, investors face significant risks from persistent cash burn and competitive pressures. The stock's valuation appears stretched at 13.46x sales despite negative earnings, requiring careful monitoring of path to profitability and execution on AI partnerships for sustained upside.

Returns comparison

Trailing returns across standard periods

About AST SpaceMobile Inc

AST SpaceMobile Inc is a satellite designer and manufacturer. The company is building the global cellular broadband network in space to operate directly with standard, unmodified mobile devices based on extensive IP and patent portfolio. AST is on a mission to eliminate the connectivity gaps faced by mobile subscribers and finally bring broadband to the billions who remain unconnected.

Read more on ASTS

About Twist Bioscience Corp

Twist Bioscience Corp is a synthetic biology company. It develops a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's DNA synthesis platform utilizes a proprietary semiconductor-based synthetic DNA manufacturing process that synthesizes DNA on silicon instead of on traditional well plastic plates to enable the production of high-quality synthetic DNA faster and affordable as well as overcomes inefficiencies. Powering cost-effective, rapid high-throughput synthesis, it enables researchers to rapidly realize opportunities ahead. Geographically, it derives a majority of revenue from the United States.

Read more on TWST