American Well Corp vs Twilio Inc — how do they compare? American Well Corp trades at $10.86 (market cap $165.58M), while Twilio Inc trades at $217.14 (market cap $32.56B). The key difference: Twilio Inc is far larger — about 196.6× American Well Corp's market cap, and American Well Corp is trading nearer its 52-week high, Twilio Inc nearer its low. Which is the better fit depends on your goals.
| AMWL | TWLO | |
|---|---|---|
Market Cap | $165.58M | $32.56B |
Sector | Health | Technology |
52-Week High | $9.91 | $236.64 |
52-Week Low | $3.78 | $92.44 |
Enterprise Value | -$9.66M | $31.29B |
Signals from Pluang's Aura AI — not financial advice
AMWL trades at $9.91, up 8.66% today, with bullish technical signals and positive momentum. The company shows improving financial trends with declining losses and strong gross margins of 52.9%, though it remains unprofitable with a -37.02% net margin. Recent news highlights Amazon's appointment of Amwell's co-founder to lead its healthcare unit, signaling industry validation.
While AMWL shows operational improvement and attractive valuation multiples (P/S 0.68, P/B 0.73), the stock faces headwinds from persistent losses and negative cash flow. Analyst consensus is cautious with a $7.25 price target below current levels, suggesting limited near-term upside despite recent positive momentum.
Twilio trades at $214.56, down 1.85% on the day, with a bullish technical outlook from moving averages but overbought RSI signals. The company shows improving fundamentals with revenue growth to $5.07B in 2025 and a return to net profitability. Recent earnings beats and positive analyst sentiment, including a Goldman Sachs buy initiation at $300 (June 24, 2026), highlight momentum in AI-driven cloud communications.
Outlook remains positive given strong earnings beats and margin expansion potential, but high valuation multiples (P/E 325.09) pose risks if growth slows. Investors face execution risks in competitive SaaS markets and sensitivity to tech sector volatility. Wall Street consensus is bullish with 75% buy ratings and a $215.14 price target, near current levels.
Trailing returns across standard periods
American Well Corp is a telehealth company enabling digital delivery of care for its customers. Its platform, Amwell, digital care delivery solution that equips health systems, health plans, government, and innovator clients with the tools to enable new models of care for their patients and members enabling care delivery across the full healthcare continuum - from primary and urgent care in the home to high acuity specialty consults, such as telestroke and telepsychiatry, in the hospital. It provides both on-demand and scheduled consultations. Its Health Plan Programs include Virtual Primary Care, Musculoskeletal Care, Dermatology Care, and Chronic Care among others and its Health System Modules include Acute Behavioral Health, ED Triage, Pediatrics and Telestroke among others.
Read more on AMWL →Twilio Inc. is a cloud-based communication platform-as-a-service company offering communication building blocks that allow for a fully customized customer engagement experience spanning voice, video, chat, and SMS messaging. It does this through various application programming interfaces, or APIs, and prebuilt solution applications aimed at improving customer engagement. The company leverages its Super Network, a global network of carrier relationships, to facilitate high-speed, cost-effective communication.
Read more on TWLO →