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Compare Amplitude Inc (AMPL) vs Vertex Pharmaceuticals Incorporated (VRTX) Price & Performance

Amplitude Inc
Vertex Pharmaceuticals Incorporated

Price performance

Price movement over the last 24 hours

Key statistics

Amplitude Inc vs Vertex Pharmaceuticals Incorporated — how do they compare? Amplitude Inc trades at $9.21 (market cap $1.22B), while Vertex Pharmaceuticals Incorporated trades at $489.74 (market cap $123.19B). The key difference: Vertex Pharmaceuticals Incorporated is far larger — about 101× Amplitude Inc's market cap, and Vertex Pharmaceuticals Incorporated is trading nearer its 52-week high, Amplitude Inc nearer its low. Which is the better fit depends on your goals.

AMPLVRTX
Market Cap
$1.22B$123.19B
Sector
TechnologyHealth
52-Week High
$13.04$529.59
52-Week Low
$5.61$366.54
Enterprise Value
$1.05B$117.93B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Amplitude Inc

AMPL trades at $9.18, down 2.13% over the past day, with a bullish technical signal from moving averages but bearish oscillators. Revenue growth is strong, reaching $343.21M in 2025, yet the company remains unprofitable with a net income margin of -25.11%. Analyst consensus is bullish with a $9.25 price target, though recent news includes multiple law firm fraud investigations and a Bank of America downgrade citing profitability concerns.

The outlook hinges on AMPL's ability to translate robust revenue growth into profitability amid competitive pressures. Investment opportunity lies in potential margin expansion and market share gains, but risks include ongoing legal scrutiny, execution challenges, and persistent negative cash flows. The stock's near-term direction will likely be driven by upcoming earnings results and clarity on the fraud allegations.

Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals (VRTX) trades at $485.39, down 2.24% today but maintains a bullish technical trend with strong support at $486. The company reported robust 2025 results with $12.00B revenue and $3.95B net income, though margins dipped slightly. Recent news highlights a strategic $10B acquisition of Crinetics Pharmaceuticals, expanding its endocrinology portfolio with potential $5B peak sales. Analyst consensus remains strongly bullish with an 83.9% buy rating and $526.50 price target.

Outlook is positive driven by earnings growth and strategic acquisitions, but risks include integration challenges from the Crinetics deal and reliance on cystic fibrosis treatments. The stock offers upside to consensus targets but faces volatility near-term.

Returns comparison

Trailing returns across standard periods

About Amplitude Inc

Amplitude Inc is pioneering a new category of software called digital optimization. The company's digital optimization system serves as the command center for businesses to connect digital products to business outcomes.

Read more on AMPL

About Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio for cystic fibrosis, where Vertex therapies remain the standard of care globally. In addition to its focus on cystic fibrosis, Vertex is diversifying its pipeline through gene-editing therapies such as CTX001 for beta-thalassemia and sickle-cell disease, small-molecule inhibitors targeting acute and chronic pain using non-opioid treatments, and small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.

Read more on VRTX